Richards KE., Xiao W., USC Pancreas Research Team, and Hill R. (2022). Cancer-Associated Fibroblasts Confer Gemcitabine Resistance to Pancreatic Cancer Cells through PTEN-Targeting miRNAs in Exosomes. Cancers 14 (11), 2812. View in PubMed.
Xiao W., Pahlavanneshan M., Eun CY., Zhang X., DeKalb C., Mahgoub B., Knaneh-Monem H., Shah S., Sohrabi A., Seidlits SK., & Hill R. (2022). Matrix stiffness mediates pancreatic cancer chemoresistance through induction of exosome hypersecretion in a cancer associated fibroblasts-tumor organoid biomimetic model. Matrix Biology Plus, Volume 14, June 2022, 100111. View in Pubmed.
Huang BZ, Liu L, Zhang J, USC Pancreas Research Team-[Okwo C, Han B, Lenz HJ, Hill R], Pandol SJ, Grossman SR, and Setiawan VW. (2022). Rising Incidence and Racial Disparities of Early-Onset Pancreatic Cancer in the United States, 1995-2018. Gastroenterology Jul;163(1):310-312.e1. View in PubMed.
Ramshani Z, Zhang C, Richards K, Chen L, Xu G, Stiles B, Hill R, Senapati S, Go D, Chang H. Extracellular Vesicle microRNA Quantification from Plasma Using an Integrated Microfluidic Device. Communications Biology 2019 May 20; 2(189). View in: Nature
Marczak S, Richards K, Ramshani Z, Smith E, Senapati S, Hill R, Go D, Chang H. Simultaneous Isolation and Preconcentration of Exosomes by Ion Concentration Polarization. Electrophoresis 2018 Feb 27; 39: 2029-38. View in: PubMed
Gifford J and Hill R. GRP78 Influences Chemoresistance and Prognosis in Cancer. Curr Drug Targets. 2018;19(6):701-708. doi: 10.2174/1389450118666170615100918. View in: PubMed
Zeleniak A*, Huang W*, Fishel M, and Hill R. PTEN-Dependent Stabilization of MTSS1 Inhibits Metastatic Phenotype in Pancreatic Ductal Adenocarcinoma. Neoplasia. 2018 Jan;20(1):12-24. doi: 10.1016/j.neo.2017.10.004. Epub 2017 Nov 23. View in: PubMed
Richards K, Zeleniak A, Fishel M, Wu J, Littlepage L, and Hill R. Cancer-Associated Fibroblast Exosomes Regulate Survival and Proliferation of Pancreatic Cancer Cells. Oncogene 2017 Mar 30;36(13):1770-1778. doi: 10.1038/onc.2016.353. Epub 2016 Sep 26. View in: PubMed
This paper has been featured on Editor’s Choice: The best of Oncogene 2016-2017
Zeleniak A, Huang W, Brinkman M, Fishel M, and Hill R. Loss of MTSS1 Results in Increased Metastatic Potential in Pancreatic Cancer. Oncotarget 2017 Mar 7;8(10):16473-16487. doi: 10.18632/oncotarget.14869. View in: PubMed
Gifford J, Huang W, Zeleniak A, Hindoyan A, Wu H, Donahue T, and Hill R. Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma. Molecular Cancer Therapeutics 2016 May;15(5):1043-52. doi: 10.1158/1535-7163.MCT-15-0774. Epub 2016 Mar 3. View in: PubMed
Taller D, Richards K, Slouka Z, Senapati S, Hill R, Go D, and Chang H. On-Chip Surface Acoustic Wave Lysis and Ion-Exchange Nanomembrane Detection of Exosomal RNA for Pancreatic Cancer Study and Diagnosis. Lab on a Chip 2015 Apr 7;15(7):1656-66. (Cover). View in: PubMed
Hill R, Li Y, Tran L, Garcia A, Hargan J, Kim C, Wang Y, Dry S, Donahue T, Herschman H, and Wu H. Delayed Progression of Pancreatic Cancer Development through Cell-Intrinsic Activity of Cox-2. Molecular Cancer Therapeutics 2012 Oct11(10):2127-2137. (Cover). View in: PubMed
Donahue T, Tran L, Hill R, Li Y, Kovochich, Calvopina J, Patel S, Hindoyan A, Farrell J, Li X, Dawson D, and Wu H. An Integrative Survival-Based Genomic and Molecular Profile of Human Pancreatic Cancer. Clinical Cancer Research. 2012 Mar 1;18(5):1352-63. View in: PubMed
Hill R, Hargan J, Kim C, Wang Y, Dawson D, Donahue T, Dry S, and Wu H. PTEN Loss Accelerates KrasG12D-Induced Pancreatic Cancer Development. Cancer Research. 2010 Sep 15;70(18):7114-24. View in: PubMed
Hill R and Wu H. PTEN, Stem Cells, and Cancer Stem Cells. Journal of Biological Chemistry. 2009 May 1;284(18):11755-9. View in: PubMed
Hill R, Song Y, Cardiff R, and Van Dyke T. Selective Evolution of Stromal Mesenchyme with p53 Loss in Response to Epithelial Tumorigenesis. Cell. 2005 Dec 16;123(6):1001-11. (Cover). View in: PubMed
Feature preview of this paper was written by Bierie B and Moses HL
Hill R, Song Y, Cardiff R, and Van Dyke T. Heterogeneous Tumor Evolution Initiated by Loss of pRb Function in a Preclinical Prostate Cancer Model. Cancer Research. 2005 Nov 15;65(22):10243-54. View in: PubMed
Book Chapters:
Richards KE, Go DB, and Hill R. Surface Acoustic Wave Lysis and Ion-Exchange Membrane Quantification of Exosomal MicroRNA. Methods Mol Biol 2017 Apr 25 1580:59-70. View in: PubMed